{"id":429,"date":"2025-04-03T09:27:28","date_gmt":"2025-04-03T01:27:28","guid":{"rendered":"http:\/\/106.52.84.14\/?p=429"},"modified":"2025-04-03T09:27:28","modified_gmt":"2025-04-03T01:27:28","slug":"%e8%84%91%e5%bd%b1%e5%83%8f%e5%9f%ba%e5%9b%a0%e7%bb%84%e5%ad%a6%ef%bc%9a%e9%9b%86%e6%88%90%e5%88%86%e6%9e%90%e4%b8%8e%e6%9c%ba%e5%99%a8%e5%ad%a6%e4%b9%a0","status":"publish","type":"post","link":"https:\/\/www.mics-ai.com\/index.php\/2025\/04\/03\/%e8%84%91%e5%bd%b1%e5%83%8f%e5%9f%ba%e5%9b%a0%e7%bb%84%e5%ad%a6%ef%bc%9a%e9%9b%86%e6%88%90%e5%88%86%e6%9e%90%e4%b8%8e%e6%9c%ba%e5%99%a8%e5%ad%a6%e4%b9%a0\/","title":{"rendered":"\u8111\u5f71\u50cf\u57fa\u56e0\u7ec4\u5b66\uff1a\u96c6\u6210\u5206\u6790\u4e0e\u673a\u5668\u5b66\u4e60"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>MICS\u79d1\u7814\u7b80\u8baf\u7b2c\u4e94\u671f<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5f71\u50cf\u57fa\u56e0\u7ec4\u5b66\u6216\u8005\u79f0\u5f71\u50cf\u9057\u4f20\u5b66\uff08Brain Imaging Genomics\/Genetics\uff09\u662f\u8111\u79d1\u5b66\u7814\u7a76\u7684\u65b0\u9886\u57df\u3002\u5f71\u50cf\u57fa\u56e0\u7ec4\u5b66\u901a\u6574\u5408\u5206\u6790\u57fa\u56e0\u7ec4\u6570\u636e\u3001\u8111\u6210\u50cf\u6570\u636e\u3001\u8bca\u65ad\u6570\u636e\u53ca\u5176\u4ed6\u7ec4\u5b66\u6570\u636e\u5982\u86cb\u767d\u8d28\u7ec4\u548c\u73af\u5883\u6570\u636e\u6765\u5206\u6790\u5927\u8111\u7ed3\u6784\u3001\u529f\u80fd\u4ee5\u53ca\u8111\u75be\u75c5\u7684\u9057\u4f20\u673a\u5236\u3002\u5b83\u7684\u591a\u7ec4\u5b66\u7814\u7a76\u7684\u7279\u70b9\u4ee5\u53ca\u6574\u5408\u5206\u6790\u7b56\u7565\uff0c\u4e3a\u63ed\u793a\u751f\u7269\u533b\u5b66\u7684\u65b0\u53d1\u73b0\u63d0\u4f9b\u4e86\u6709\u529b\u7684\u65b9\u6cd5\u3002\u540c\u65f6\uff0c\u9274\u4e8e\u5176\u591a\u5b66\u79d1\u4ea4\u53c9\u7684\u7279\u70b9\uff0c\u673a\u5668\u5b66\u4e60\u6280\u672f\u5728\u5176\u4e2d\u53d1\u6325\u4e86\u91cd\u8981\u7684\u4f5c\u7528\u3002\u8be5\u8bba\u6587\u56de\u987e\u4e86\u8fc7\u53bb\u5341\u591a\u5e74\u6765\u5f71\u50cf\u57fa\u56e0\u7ec4\u5b66\u4e2d\u7684\u673a\u5668\u5b66\u4e60\u65b9\u6cd5\u3002<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" src=\"http:\/\/106.52.84.14\/wp-content\/uploads\/2025\/04\/image-85-7-12-1-1.jpg\" alt=\"\" class=\"wp-image-430\"\/><\/figure>\n<\/div>\n\n\n<p class=\"has-text-align-center wp-block-paragraph\">\u56fe 1&nbsp;\u672c\u7efc\u8ff0\u7684\u4e3b\u8981\u5185\u5bb9<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8be5\u7efc\u8ff0\u8bba\u6587\u5305\u62ec\u4e09\u65b9\u9762\u4e3b\u8981\u5185\u5bb9\uff1a\u4e00\uff0c\u5f71\u50cf\u57fa\u56e0\u7ec4\u5b66\u7814\u7a76\u4e2d\u7684\u79d1\u5b66\u95ee\u9898\uff1b\u4e8c\uff0c\u5f71\u50cf\u57fa\u56e0\u7ec4\u5b66\u7814\u7a76\u7684\u5e94\u7528\uff0c\u4ee5\u53ca\u5176\u6d89\u53ca\u7684\u6570\u636e\u7c7b\u578b\uff1b\u4e09\uff0c\u5f71\u50cf\u57fa\u56e0\u7ec4\u5b66\u4e2d\u7684\u673a\u5668\u5b66\u4e60\u65b9\u6cd5\u3002\u5728\u672c\u6b21\u7b80\u8baf\u4e2d\uff0c\u6211\u4eec\u4e3b\u8981\u4ecb\u7ecd\u5f71\u50cf\u57fa\u56e0\u7ec4\u5b66\u4ee5\u53ca\u5176\u4e2d\u6d89\u53ca\u7684\u673a\u5668\u5b66\u4e60\u7b97\u6cd5\uff0c\u5177\u4f53\u7ec6\u8282\u53ef\u67e5\u9605\u6587\u540e\u53c2\u8003\u6587\u732e\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u4e00\u3001\u9057\u4f20\u6982\u7387\u6216\u9057\u4f20\u53ef\u80fd\u6027\uff08Heritability\uff09<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u9057\u4f20\u6982\u7387\u7528\u6765\u4f30\u8ba1\u67d0\u4e2a\u6027\u72b6\uff08Brain Imaging Quantitative Traits, QT\uff09\u7684\u9057\u4f20\u53ef\u80fd\u6027\uff0c\u4e5f\u5c31\u662f\u8be5\u6027\u72b6\u6709\u591a\u5927\u7684\u6982\u7387\u53d7\u9057\u4f20\u56e0\u7d20\u7684\u5f71\u54cd\uff0c\u5e76\u5c06\u8be5\u5f71\u54cd\u91cf\u5316\u3002\u6d89\u53ca\u7684\u9057\u4f20\u56e0\u7d20\u5305\u542b\u57fa\u56e0\u4f4d\u70b9\u53d8\u5f02\uff08Single Nucleotide Polymorphisms, SNP\uff09\u3001\u5355\u57fa\u56e0\u53d8\u5f02\u3001\u591a\u57fa\u56e0\u53d8\u5f02\u3001\u4ee5\u53ca\u57fa\u56e0-\u57fa\u56e0\u4ea4\u4e92\u5f02\u5e38\u3002\u9057\u4f20\u6982\u7387\u7684\u7814\u7a76\u662f\u5f71\u50cf\u57fa\u56e0\u7ec4\u5b66\u7814\u7a76\u7684\u57fa\u7840\uff0c\u5b83\u662f\u5f71\u50cf\u9057\u4f20\u5b66\u7814\u7a76\u5f97\u4ee5\u4ece\u5047\u60f3\u8d70\u5411\u5b9e\u8df5\u7684\u524d\u63d0\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u9057\u4f20\u6982\u7387\u7684\u7814\u7a76\u4ece\u65e9\u671f\u57fa\u4e8e\u53cc\u80de\u80ce\u6216\u8005\u7cfb\u8c31\u6cd5\uff0c\u53d1\u5c55\u5230\u540e\u6765\u57fa\u4e8e\u5168\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u6570\u636e\u7684\u7814\u7a76\u3002\u8fd9\u4e9b\u7814\u7a76\u4ece\u4e0d\u540c\u7a0b\u5ea6\u8bc1\u660e\u4e86\u5927\u8111\u7684\u7ed3\u6784\u548c\u529f\u80fd\uff0c\u4ee5\u53ca\u5176\u53d1\u80b2\u548c\u9000\u5316\u53d7\u5355\u4e2aSNP\u3001\u591a\u4e2aSNP\u3001\u5355\u57fa\u56e0\u3001\u591a\u57fa\u56e0\u53ca\u57fa\u56e0\u4ea4\u4e92\u7684\u5f71\u54cd\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u4e8c\u3001\u5f71\u50cf\u57fa\u56e0\u7ec4\u5b66\u5173\u8054\u7814\u7a76<\/strong><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" src=\"http:\/\/106.52.84.14\/wp-content\/uploads\/2025\/04\/image-85-7-13-1-1.jpg\" alt=\"\" class=\"wp-image-431\"\/><\/figure>\n<\/div>\n\n\n<p class=\"has-text-align-center wp-block-paragraph\">\u56fe 2&nbsp;\u5f71\u50cf\u57fa\u56e0\u7ec4\u5b66\u5173\u8054\u5206\u6790<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6027\u72b6\u7684\u9057\u4f20\u53ef\u80fd\u6027\u7814\u7a76\u53ef\u4ee5\u63ed\u9732\u67d0\u4e2a\u6027\u72b6\u53d7\u9057\u4f20\u56e0\u7d20\u5f71\u54cd\u7684\u5927\u5c0f\uff0c\u4f46\u662f\u5374\u65e0\u6cd5\u544a\u77e5\u6211\u4eec\u8be5\u6027\u72b6\u5230\u5e95\u662f\u7531\u54ea\u4e2a\u57fa\u56e0\u6216\u8005\u4f4d\u70b9\u7684\u53d8\u5f02\u6240\u5f15\u8d77\u3002\u5f71\u50cf\u57fa\u56e0\u7ec4\u5b66\u4e2d\u7684\u5173\u8054\u5206\u6790\u5c31\u662f\u7528\u6765\u89e3\u7b54\u8be5\u95ee\u9898\u3002\u6839\u636e\u6587\u4e2d\u4ecb\u7ecd\uff0c\u6b64\u90e8\u5185\u5bb9\u4e3b\u8981\u6d89\u53ca\u4e09\u79cd\u7b56\u7565\uff1a1\uff0c\u76ee\u6807QT\u5206\u6790\uff08\u56fe2\u84dd\u8272\u6846\uff09\uff1b2\uff0c\u76ee\u6807SNP\u5206\u6790\uff08\u56fe2\u7ea2\u8272\u6846\uff09\uff1b3\uff0c\u5168\u8111-\u5168\u57fa\u56e0\u7ec4\u5173\u8054\u5206\u6790\uff08\u56fe2\u5de6\u4e0aheatmap\uff09\u3002\u65e9\u671f\u7684\u5f71\u50cf\u57fa\u56e0\u7ec4\u5b66\u5173\u8054\u5206\u6790\u4e3b\u8981\u57fa\u4e8e\u8fd9\u4e09\u79cd\u7b56\u7565\u8fdb\u884c\u7814\u7a76\u3002\u4f5c\u8005\u5728\u6587\u4e2d\u8be6\u7ec6\u4ecb\u7ecd\u4e86\u8fd9\u4e09\u79cd\u7814\u7a76\u7b56\u7565\u7684\u7814\u7a76\u65b9\u6cd5\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u4e09\u3001\u5f71\u50cf\u57fa\u56e0\u7ec4\u5b66\u673a\u5668\u5b66\u4e60\u65b9\u6cd5<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u9274\u4e8eSNP\u6570\u636e\u548c\u8111\u6210\u50cf\u6570\u636e\u6570\u76ee\u5de8\u5927\u4ee5\u53ca\u4e8c\u8005\u9519\u7efc\u590d\u6742\u7684\u5173\u7cfb\uff0c\u5355\u53d8\u91cf\u5206\u6790\u7b56\u7565\u68c0\u6d4b\u80fd\u529b\u6709\u9650\u3002\u56e0\u6b64\u9700\u8981\u8fdb\u884c\u591a\u53d8\u91cf\u65b9\u6cd5\u7684\u5f00\u53d1\u7814\u7a76\u3002\u8fc7\u53bb\u5341\u5e74\u63d0\u51fa\u4e86\u591a\u79cd\u591a\u53d8\u91cf\u673a\u5668\u5b66\u4e60\u65b9\u6cd5\uff0c\u5c24\u5176\u662f\u7ed3\u5408\u7a00\u758f\u5b66\u4e60\u6280\u672f\u548c\u56de\u5f52\u6280\u672f\u3001\u5178\u578b\u76f8\u5173\u5206\u6790\u7684\u5f71\u50cf\u57fa\u56e0\u7ec4\u5b66\u65b9\u6cd5\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">1.&nbsp;\u7a00\u758f\u591a\u53d8\u91cf\u56de\u5f52\uff08Sparse&nbsp;Multivariate&nbsp;Regression\uff09<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e3a\u4e86\u7814\u7a76\u591a\u4e2aSNP\u548c\u5355\u4e2a\u6216\u8005\u5c11\u8bb8QT\u4e4b\u95f4\uff08\u6216\u8005\u591a\u4e2aQT\u548c\u5355\u4e2a\u6216\u5c11\u8bb8SNP\uff09\u7684\u5173\u8054\uff0c\u6700\u76f4\u63a5\u4e14\u6709\u6548\u7684\u65b9\u6cd5\u5f53\u5c5e\u56de\u5f52\u6280\u672f\u3002\u8be5\u7c7b\u65b9\u6cd5\u7684\u6a21\u578b\u53ef\u6982\u62ec\u4e3a\u5982\u4e0b\u6a21\u578b\uff1a<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" src=\"http:\/\/106.52.84.14\/wp-content\/uploads\/2025\/04\/image-85-1-18-17-1-1.png\" alt=\"\" class=\"wp-image-432\"\/><\/figure>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\">\u5176\u4e2d\u7b2c\u4e00\u9879\u4e3a\u56de\u5f52\u635f\u5931\u51fd\u6570\uff0c\u7b2c\u4e8c\u9879\u4e3a\u7ea6\u675f\u9879\u6765\u8fdb\u884c\u7279\u5f81\u9009\u62e9\u3002X\u901a\u5e38\u5bf9\u5e94SNP\u6570\u636e\uff0cY\u5bf9\u5e94QT\u6570\u636e\uff0c<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"http:\/\/106.52.84.14\/wp-content\/uploads\/2025\/04\/image-85-1-18-18-1-1.png\" alt=\"\" class=\"wp-image-433\"\/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">\u662f\u6743\u91cd\u7cfb\u6570\uff0c\u5b83\u7684\u7edd\u5bf9\u503c\u5927\u5c0f\u5bf9\u5e94\u7740\u81ea\u53d8\u91cf\u5bf9\u56e0\u53d8\u91cf\u5f71\u54cd\u7684\u7a0b\u5ea6\u3002\u5728\u8fc7\u53bb\u5341\u5e74\u4e2d\uff0c\u7814\u7a76\u8005\u63d0\u51fa\u4e86\u591a\u79cd\u635f\u5931\u51fd\u6570\u548c\u7ea6\u675f\u9879\u6765\u66f4\u597d\u66f4\u5168\u66f4\u7b26\u5408\u771f\u5b9e\u60c5\u51b5\u5730\u68c0\u6d4bSNP\u548cQT\u4e4b\u95f4\u7684\u5173\u8054\u3002\u4f5c\u8005\u5728\u6587\u4e2d\u5206\u522b\u4ecb\u7ecd\u4e86\u591a\u79cd\u635f\u5931\u51fd\u6570\uff0c\u5982\u5355\u4efb\u52a1\u56de\u5f52\u635f\u5931\u51fd\u6570\u3001\u591a\u4efb\u52a1\u56de\u5f52\u635f\u5931\u51fd\u6570\u3001\u504f\u6700\u5c0f\u4e8c\u4e58\u56de\u5f52\u635f\u5931\u51fd\u6570\u3001\u51cf\u79e9\u56de\u5f52\u635f\u5931\u51fd\u6570\u548c\u8d1d\u53f6\u65af\u56de\u5f52\u635f\u5931\u51fd\u6570\u7b49\uff1b\u4e5f\u4ecb\u7ecd\u4e86\u591a\u79cd\u7279\u5f81\u9009\u62e9\u76ee\u7684\u7684\u7ea6\u675f\u51fd\u6570\uff0c\u5982Lasso\u3001Group Lasso\u3001Graphical Lasso\u7b49\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">2.&nbsp;\u53cc\u8fb9\u591a\u53d8\u91cf\u5173\u8054\u5206\u6790\uff08Bimultivariate&nbsp;Correlation\uff09<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" src=\"http:\/\/106.52.84.14\/wp-content\/uploads\/2025\/04\/image-85-1-18-19-1-1.png\" alt=\"\" class=\"wp-image-434\"\/><\/figure>\n<\/div>\n\n\n<p class=\"has-text-align-center wp-block-paragraph\">\u56fe 3&nbsp;\u5178\u578b\u76f8\u5173\u5206\u6790<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e0e\u56de\u5f52\u6280\u672f\u4ec5\u80fd\u8fdb\u884c\u5355\u4fa7\u7684\u7279\u5f81\u9009\u62e9\u76f8\u6bd4\uff0c\u8be5\u7c7b\u65b9\u6cd5\u53ef\u4ee5\u540c\u65f6\u8fdb\u884c\u53cc\u8fb9\u7279\u5f81\u9009\u62e9\u3002\u56e0\u6b64\u53cc\u8fb9\u591a\u53d8\u91cf\u5173\u8054\u5206\u6790\u66f4\u7b26\u5408\u5f71\u50cf\u57fa\u56e0\u7ec4\u5b66\u7684\u6570\u636e\u7279\u5f81\uff0c\u5373SNP\u548cQT\u5747\u4e3a\u591a\u7ef4\u4e14\u7ef4\u5ea6\u975e\u5e38\u9ad8\u3002\u5728\u8fc7\u53bb5\u5e74\u4e2d\uff0c\u8be5\u7c7b\u65b9\u6cd5\u7814\u7a76\u5728\u5f71\u50cf\u57fa\u56e0\u7ec4\u5b66\u9886\u57df\u53d1\u5c55\u8fc5\u901f\u3002\u5982\u56fe3\u6240\u793a\uff0c\u8be5\u7c7b\u65b9\u6cd5\u53ef\u6982\u62ec\u4e3a\u5982\u4e0b\u6a21\u578b\uff1a<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" src=\"http:\/\/106.52.84.14\/wp-content\/uploads\/2025\/04\/image-85-1-19-10-1-1.png\" alt=\"\" class=\"wp-image-435\"\/><\/figure>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\">\u901a\u5e38\uff0cX\u548cY\u5206\u522b\u5bf9\u5e94SNP\u548cQT\u6570\u636e\uff0cu\u548cv\u662f\u5178\u578b\u6743\u91cd\uff08Canonical Weight\u6216\u8005Canonical Loading\uff09\u3002\u516c\u5f0f\u4e2d\u7684\u7b2c\u4e00\u9879\u662f\u5178\u578b\u76f8\u5173\u635f\u5931\u51fd\u6570\uff0c\u7b2c\u4e8c\u9879\u662f\u7ea6\u675f\u9879\u7528\u6765\u8fdb\u884c\u7279\u5f81\u9009\u62e9\u3002\u4f5c\u8005\u5728\u6587\u4e2d\u4ecb\u7ecd\u4e86\u591a\u79cd\u8be5\u6a21\u578b\u7684\u53d8\u79cd\u4ee5\u53ca\u5b83\u4eec\u5404\u81ea\u7684\u7279\u70b9\u3002\u5982\u9762\u5411\u7279\u5f81\u4e4b\u95f4\u76f8\u4e92\u5173\u7cfb\u7684Graphical Lasso\u548cGroup Lasso\uff0c\u4ee5\u53ca\u9762\u5411\u7eb5\u5411\u548c\u591a\u6a21\u6001\u7684\u7ea6\u675f\u7b49\u7279\u5f81\u9009\u62e9\u6280\u672f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">3.&nbsp;\u878d\u5408SNP\u548cQT\u7684\u9884\u6d4b\u65b9\u6cd5<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u987e\u540d\u601d\u4e49\uff0c\u8be5\u90e8\u5206\u65b9\u6cd5\u7814\u7a76\u4e3b\u8981\u6d89\u53ca\u878d\u5408SNP\u548cQT\u6765\u7cbe\u51c6\u5730\u9884\u6d4b\u8ba4\u77e5\u5f97\u5206\u548c\u8bca\u65ad\u7ed3\u679c\u3002\u5982\u56fe4\u6240\u793a\uff0c\u4f5c\u8005\u5728\u6587\u4e2d\u4ecb\u7ecd\u4e86\u51e0\u79cd\u878d\u5408\u65b9\u6cd5\uff0c\u6bd4\u5982\u4f7f\u7528\u5927\u8111\u76ae\u5c42\u539a\u5ea6\u3001\u8868\u9762\u9762\u79ef\u4ee5\u53caSNP\u6570\u636e\u6765\u540c\u65f6\u9884\u6d4b\u8ba4\u77e5\u5f97\u5206\u548c\u8bca\u65ad\u7c7b\u522b\uff1b\u4ee5\u5927\u8111QT\u4e3a\u4e2d\u95f4\u7ea6\u675f\uff0c\u5e76\u4f7f\u7528SNP\u6570\u636e\u6765\u9884\u6d4b\u8bca\u65ad\u7ed3\u679c\uff1b\u4ee5\u53ca\u6839\u636e\u878d\u5408\u65f6\u4e0d\u540c\u6570\u636e\u7c7b\u578b\u5bf9\u8f93\u51fa\u8d21\u732e\u7684\u4e0d\u540c\uff0c\u8bbe\u8ba1\u7684\u7b80\u5355\u878d\u5408\u7b56\u7565\u548c\u81ea\u9002\u5e94\u878d\u5408\u7b56\u7565\u7b49\u65b9\u6cd5\u3002<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" src=\"http:\/\/106.52.84.14\/wp-content\/uploads\/2025\/04\/image-85-7-14-1-1.jpg\" alt=\"\" class=\"wp-image-436\"\/><\/figure>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\">\u56fe 4&nbsp;\u5f71\u50cf\u57fa\u56e0\u7ec4\u9884\u6d4b<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6700\u540e\uff0c\u5728\u4ecb\u7ecd\u4e86\u591a\u53d8\u91cf\u56de\u5f52\u548c\u53cc\u8fb9\u591a\u53d8\u91cf\u5178\u578b\u76f8\u5173\u5206\u6790\u6280\u672f\u540e\uff0c\u4f5c\u8005\u4ecb\u7ecd\u4e86\u51e0\u79cd\u878d\u5408\u56de\u5f52\u6280\u672f\u548c\u5178\u578b\u76f8\u5173\u5206\u6790\u7684\u65b9\u6cd5\uff0c\u8fd9\u7c7b\u6a21\u578b\u80fd\u591f\u53d1\u73b0SNP\u548cQT\u5173\u8054\u7684\u540c\u65f6\uff0c\u4f7f\u5f97\u4e8c\u8005\u4e0e\u8bca\u65ad\u4fe1\u606f\u76f8\u5173\uff0c\u8fd9\u6837\u53ef\u5f97\u5230\u66f4\u5f3a\u7684\u5173\u8054\u4ee5\u53ca\u51cf\u5c11\u8fc7\u62df\u5408\u3002&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u603b\u7684\u6765\u8bf4\uff0c\u5f71\u50cf\u57fa\u56e0\u7ec4\u5b66\u662f\u8f83\u65b0\u7684\u4e00\u4e2a\u7814\u7a76\u65b9\u5411\uff0c\u5176\u6d89\u53ca\u7684\u8bb8\u591a\u95ee\u9898\u5c1a\u6ca1\u6709\u5f88\u597d\u5730\u89e3\u51b3\u3002\u4f5c\u8005\u5bf9\u6b64\u5728\u8bba\u6587\u4e2d\u8fdb\u884c\u4e86\u8be6\u7ec6\u5168\u9762\u7684\u603b\u7ed3\u3002\u5728\u672c\u6b21\u7b80\u8baf\u4e2d\uff0c\u6211\u4eec\u4ec5\u5bf9\u6587\u4e2d\u6d89\u53ca\u7684\u5f71\u50cf\u57fa\u56e0\u7ec4\u5b66\u57fa\u7840\u95ee\u9898\u548c\u65b9\u6cd5\u8fdb\u884c\u4e86\u6982\u7565\u6027\u7684\u4ecb\u7ecd\uff0c\u5f88\u591a\u76f8\u5173\u7684\u7ec6\u8282\u65e0\u6cd5\u9762\u9762\u4ff1\u5230\u3002\u5982\u82e5\u611f\u5174\u8da3\uff0c\u53ef\u67e5\u9605\u6587\u540e\u7684\u53c2\u8003\u6587\u732e\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u53c2\u8003\u6587\u732e\uff1a<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">[1]&nbsp;Li Shen, Paul M Thompson. Brain Imaging Genomics: Integrated Analysis and Machine Learning. Proceedings of the IEEE. IEEE, 2019. 108(1): 125-162.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>&nbsp;&nbsp;<\/strong>\u672c\u6587\u4f5c\u8005\uff1a\u675c\u78ca&nbsp;&nbsp;&nbsp; &nbsp;&nbsp; &nbsp;&nbsp; &nbsp; &nbsp;&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5355 &nbsp; &nbsp; &nbsp; \u4f4d\uff1a\u897f\u5317\u5de5\u4e1a\u5927\u5b66<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p class=\"wp-block-paragraph\">\u533b\u5b66\u56fe\u50cf\u8ba1\u7b97\u9752\u5e74\u7814\u8ba8\u4f1a\uff08Medical Imaging Computing Seminar\uff0cMICS\uff09\u521b\u7acb\u4e8e2014\u5e74\uff0c\u5176\u5b97\u65e8\u662f\u4e3a\u533b\u5b66\u56fe\u50cf\u9886\u57df\u7684\u534e\u4eba\u9752\u5e74\u5b66\u8005\u63d0\u4f9b\u5b66\u672f\u4ea4\u6d41\u5e73\u53f0\uff0c\u589e\u8fdb\u76f8\u4e92\u4e4b\u95f4\u7684\u4e86\u89e3\u548c\u53cb\u8c0a\uff0c\u5e2e\u52a9\u9752\u5e74\u5b66\u8005\u878d\u5165\u5b66\u672f\u7814\u7a76\u5927\u5bb6\u5ead\u3002MICS\u805a\u7126\u4e8e\u8fd1\u4e24\u5e74\u5185\u7684\u533b\u5b66\u56fe\u50cf\u8ba1\u7b97\u9886\u57df\u539f\u521b\u7814\u7a76\uff0c\u6b22\u8fce\u533b\u5b66\u56fe\u50cf\u5904\u7406\u3001\u8ba1\u7b97\u673a\u89c6\u89c9\u3001\u4eba\u5de5\u667a\u80fd\u7b49\u65b0\u7406\u8bba\u3001\u65b0\u65b9\u6cd5\u3001\u65b0\u5e94\u7528\u7684\u5c55\u793a\uff0c\u4ee5\u53ca\u5f71\u50cf\u4e0e\u4e34\u5e8a\u533b\u5b66\u3001\u57fa\u7840\u533b\u5b66\u6df1\u5ea6\u4ea4\u53c9\u7684\u7a81\u7834\u6027\u8fdb\u5c55\u62a5\u544a\u3002\u9996\u5c4aMICS\u5728\u533b\u5b66\u56fe\u50cf\u9886\u57df\u8457\u540d\u5b66\u8005\u3001\u5317\u5361\u7f57\u6765\u7eb3\u5927\u5b66\u6559\u5802\u5c71\u5206\u6821\u6c88\u5b9a\u521a\u6559\u6388\u7684\u5021\u8bae\u4e0b\uff0c\u4e8e2014\u5e7412\u6708\u5728\u6df1\u5733\u5927\u5b66\u4e3e\u884c\u3002\u7ecf\u8fc72015\uff08\u6d4e\u5357\uff09\u30012016\uff08\u5e7f\u5dde\uff09\u30012017\uff08\u4e0a\u6d77\uff09\u30012018\uff08\u5357\u4eac\uff09\u30012019\uff08\u82cf\u5dde\uff09\u7684\u84ec\u52c3\u53d1\u5c55\uff0cMICS\u4ece\u53c2\u4f1a\u4eba\u6570\u4e0d\u8db3\u767e\u4eba\u5230\u5438\u5f15\u4e0a\u5343\u540d\u4e13\u5bb6\u5b66\u8005\u53c2\u4e0e\uff0c\u5df2\u8fc5\u901f\u6210\u4e3a\u5168\u56fd\u533b\u5b66\u56fe\u50cf\u8ba1\u7b97\u9886\u57df\u6700\u5177\u5f71\u54cd\u529b\u7684\u6d3b\u52a8\u4e4b\u4e00\u30022020\u5e74\u7684MICS\u4f1a\u8bae\u5c06\u4e8e7\u670818~19\u65e5\u5728\u5927\u8fde\u4e3e\u529e\uff0c\u6b22\u8fce\u5168\u7403\u540c\u9053\u4e13\u5bb6\u548c\u540c\u5b66\u5171\u805a\u5b66\u672f\u76db\u5bb4\uff01<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" src=\"http:\/\/106.52.84.14\/wp-content\/uploads\/2025\/04\/image-85-1-19-11-1-1.png\" alt=\"\" class=\"wp-image-437\"\/><\/figure>\n<\/div>\n\n\n<p class=\"has-text-align-center wp-block-paragraph\">\u201c\u533b\u5b66\u56fe\u50cf\u8ba1\u7b97\u9752\u5e74\u7814\u8ba8\u4f1a\u201d\u5fae\u4fe1\u516c\u4f17\u53f7<\/p>\n","protected":false},"excerpt":{"rendered":"<p>MICS\u79d1\u7814\u7b80\u8baf\u7b2c\u4e94\u671f \u5f71\u50cf\u57fa\u56e0\u7ec4\u5b66\u6216\u8005&hellip;<\/p>\n","protected":false},"author":1,"featured_media":430,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-429","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-7"],"_links":{"self":[{"href":"https:\/\/www.mics-ai.com\/index.php\/wp-json\/wp\/v2\/posts\/429","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.mics-ai.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.mics-ai.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.mics-ai.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.mics-ai.com\/index.php\/wp-json\/wp\/v2\/comments?post=429"}],"version-history":[{"count":0,"href":"https:\/\/www.mics-ai.com\/index.php\/wp-json\/wp\/v2\/posts\/429\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.mics-ai.com\/index.php\/wp-json\/wp\/v2\/media\/430"}],"wp:attachment":[{"href":"https:\/\/www.mics-ai.com\/index.php\/wp-json\/wp\/v2\/media?parent=429"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.mics-ai.com\/index.php\/wp-json\/wp\/v2\/categories?post=429"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.mics-ai.com\/index.php\/wp-json\/wp\/v2\/tags?post=429"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}