![\"\"](\"http:\/\/106.52.84.14\/wp-content\/uploads\/2025\/04\/image-85-8-15-1-1.png\")
<\/figure>\n<\/div>\n\n\n
\u56fe1. \u7b2c\u4e00\u3001\u4e8c\u884c\uff1a\u5a74\u513f\u57282\u5468\u523012\u4e2a\u6708\u9f84\u671f\u95f4\u7684T1\u52a0\u6743\u548cT2\u52a0\u6743\u8111\u56fe\u50cf\uff1b\u7b2c\u4e09\u884c\uff1aT1\u52a0\u6743\u56fe\u50cf\u4e2d\u8111\u7ec4\u7ec7\u7684\u7070\u5ea6\u5206\u5e03\uff0c\u5176\u4e2d\u767d\u8d28\u548c\u7070\u8d28\u4f53\u7d20\u503c\u57286\u6708\u9f84\u65f6\u9ad8\u5ea6\u91cd\u53e0\u3002\u56e0\u6b64\uff0c\u5728\u5927\u7ea66\u6708\u9f84\u65f6\uff0cT1\u52a0\u6743\u548cT2\u52a0\u6743\u8111\u56fe\u50cf\u663e\u793a\u51fa\u6700\u4f4e\u7684\u7ec4\u7ec7\u5bf9\u6bd4\u5ea6\uff0c\u8fd9\u610f\u5473\u7740\u7ec4\u7ec7\u5206\u5272\u6700\u5177\u6311\u6218\u6027\u3002<\/p>\n\n\n\n
\u5728iSeg-2017\u6311\u6218\u8d5b\u4e2d\uff0c\u7814\u7a76\u4eba\u5458\u88ab\u9080\u8bf7\u5bf96\u6708\u9f84\u5a74\u513f\u8111MR\u56fe\u50cf\u8fdb\u884c\u767d\u8d28\uff0c\u7070\u8d28\u548c\u8111\u810a\u6db2\u5206\u5272\u3002\u670921\u4e2a\u56fd\u9645\u56e2\u961f\u5728iSeg-2017\u7f51\u7ad9\u4e0a\u63d0\u4ea4\u4e86\u4ed6\u4eec\u7684\u7ed3\u679c\u3002\u6709\u8da3\u7684\u662f\uff0c\u5176\u4e2d20\u4e2a\u56e2\u961f\u5747\u4f7f\u7528\u5377\u79ef\u795e\u7ecf\u7f51\u7edc\u8fdb\u884c\u5206\u5272\uff0c\u800c\u53ea\u67091\u4e2a\u56e2\u961f\u4f7f\u7528\u7ecf\u5178\u7684\u57fa\u4e8e\u591a\u56fe\u8c31\uff08Multi-atlas\uff09\u7684\u5206\u5272\u65b9\u6cd5\u3002\u5728\u4f7f\u7528\u5377\u79ef\u795e\u7ecf\u7f51\u7edc\u768420\u4e2a\u56e2\u961f\u4e2d\uff0c8\u4e2a\u56e2\u961f\u91c7\u7528\u4e86U-Net\u67b6\u6784\u3002\u6311\u6218\u8d5b\u6839\u636e\u56db\u65b9\u9762\u6307\u6807\uff1a\u5206\u5272\u7cbe\u5ea6\uff08Dice\uff09\uff0c\u8c6a\u65af\u591a\u592b\u8ddd\u79bb\uff08HD95\uff09\uff0c\u5e73\u5747\u8868\u9762\u8ddd\u79bb\uff08ASD\uff09\u548c\u6c9f\u56de\u66f2\u7ebf\u8ddd\u79bb\uff0c\u6765\u8bc4\u4f30\u53c2\u8d5b\u65b9\u6cd5\u3002\u7cbe\u5ea6\u6700\u9ad8\u7684\u524d8\u4f4d\u7684\u56e2\u961f\u4e2d\u67097\u4e2a\u91c7\u7528\u4e86\u57fa\u4e8e\u6df1\u5ea6\u5b66\u4e60\u7684\u7b97\u6cd5\u3002\u7531\u4e8e\u4f7f\u7528\u4e86GPU\uff0c\u5927\u591a\u6570\u7b97\u6cd5\u5bf9\u8111MR\u56fe\u50cf\u5206\u5272\u5904\u7406\u65f6\u95f4\u57285-10\u79d2\u4e4b\u95f4\u3002\u5c31\u5168\u8111\u5206\u5272\u7cbe\u5ea6\uff08Dice\uff0cHD95\uff0cASD\uff09\u4ee5\u53ca\u5c40\u90e8\u5206\u5272\u7cbe\u5ea6\uff08\u6c9f\u56de\u66f2\u7ebf\u8ddd\u79bb\uff09\u800c\u8a00\uff0c\u524d8\u4f4d\u65b9\u6cd5\u4e2d\u6ca1\u6709\u4e00\u79cd\u65b9\u6cd5\u6bd4\u5176\u4ed6\u6240\u6709\u65b9\u6cd5\u90fd\u5177\u6709\u663e\u8457\u7684\u7edf\u8ba1\u5b66\u5dee\u5f02\u3002\u6839\u636e\u56fe2\u4e2d\u7684\u8bef\u5dee\u56fe\uff0c\u8fd9\u4e9b\u65b9\u6cd5\u5728\u76ae\u8d28\u533a\u57df\u5206\u5272\u6027\u80fd\u90fd\u8f83\u5dee\u3002\u56e0\u6b64\uff0c\u4ecd\u6709\u63d0\u5347\u7684\u7a7a\u95f4\u3002<\/p>\n\n\n
![\"\"](\"http:\/\/106.52.84.14\/wp-content\/uploads\/2025\/04\/image-85-4-18-1-1.jpg\")
<\/figure>\n<\/div>\n\n\n\u56fe2. \u8bef\u5dee\u56fe\uff1a\u524d\u516b\u540d\u65b9\u6cd5\u5728\u76ae\u8d28\u4e0b\u533a\u57df\u8bef\u5dee\u4e0d\u5927\uff0c\u4f46\u76ae\u8d28\u533a\u57df\u7684\u8bef\u5dee\u660e\u663e\u3002\u524d\u516b\u540d\u65b9\u6cd5\u7684\u5e73\u5747\u8bef\u5dee\u56fe\u4e3a\u53f3\u4e0b\u65b9\u3002\u7ea2\u8272\uff1a\u5bb9\u6613\u51fa\u9519\u533a\u57df\uff1b\u84dd\u8272\uff1a\u6b63\u786e\u5206\u5272\u533a\u57df\u3002
\u00a0
\u9488\u5bf9\u8fd9\u4e9b\u5206\u5272\u65b9\u6cd5\u7684\u5f31\u70b9\uff0c\u4f5c\u8005\u7ed9\u51fa\u4e86\u5206\u6790\uff0c\u5e76\u6307\u51fa\u4e86\u53ef\u80fd\u7684\u6539\u8fdb\u65b9\u5411\u3002\u9996\u5148\uff0c\u6240\u6709\u65b9\u6cd5\u76f4\u63a5\u5e94\u7528\u6210\u719f\u7684\u6a21\u578b\uff08\u4f8b\u5982\uff0cU-Net\uff09\u6765\u5e94\u5bf9\u6311\u6218\uff0c\u5e76\u672a\u8003\u8651\u5a74\u5e7c\u513f\u5927\u8111\u7684\u4efb\u4f55\u5148\u9a8c\u77e5\u8bc6\u3002\u4f8b\u5982\uff0c\u4eba\u7c7b\u7684\u5927\u8111\u76ae\u8d28\u539a\u5ea6\u662f\u5728\u4e00\u5b9a\u8303\u56f4\u5185\u7684[1\uff0c3]\u3002\u7279\u522b\u662f\u7531\u4e8e6\u6708\u9f84\u7684\u5a74\u513f\u8111MRI\u4e2d\u767d\u8d28\u548c\u7070\u8d28\u4e4b\u95f4\u7684\u5bf9\u6bd4\u5ea6\u4f4e\uff0c\u767d\u8d28\/\u7070\u8d28\u4f53\u7d20\u53ef\u80fd\u4f1a\u88ab\u9519\u8bef\u5206\u5272\u3002\u5728iSeg-2017\u4e2d\u56fe\u50cf\u5206\u8fa8\u7387\u4e3a1\u00d71\u00d71mm3\uff0c\u5c3d\u7ba1\u4e00\u4e2a\u4f53\u7d20\u9519\u8bef\u5bf9Dice\u6216HD95\u7684\u5f71\u54cd\u53ef\u5ffd\u7565\u4e0d\u8ba1\uff0c\u4f46\u5b83\u5c06\u5bfc\u81f4\u76ae\u8d28\u539a\u5ea6\u4ea7\u751f\u00b11mm\u4f30\u8ba1\u8bef\u5dee\u3002\u56fe3\u663e\u793a\u4e86\u7531\u5176\u4e2d\u4e00\u4e2a\u56e2\u961f\u83b7\u5f97\u7684\u4e00\u4f8b\u5206\u5272\u7ed3\u679c\u3002\u5728\u6ca1\u6709\u89e3\u5256\u5b66\u5148\u9a8c\u77e5\u8bc6\u6307\u5bfc\u7684\u60c5\u51b5\u4e0b\uff0c\u8be5\u65b9\u6cd5\u7684\u5206\u5272\u7ed3\u679c\u6240\u91cd\u5efa\u7684\u5185\u76ae\u5c42\u8868\u9762\u4e2d\u5b58\u5728\u8bb8\u591a\u7f3a\u5931\u7684\u8111\u56de\u3002\u56e0\u6b64\uff0c\u4f30\u8ba1\u7684\u76ae\u8d28\u539a\u5ea6\u5f02\u5e38\u5730\u539a\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u8fd9\u7c7b\u9519\u8bef\u5c06\u96be\u4ee5\u7cbe\u786e\u8868\u5f81\u5927\u8111\u53d1\u80b2\u5c5e\u6027\uff0c\u6bd4\u5982\u76ae\u8d28\u539a\u5ea6\uff0c\u6c9f\u56de\u53d1\u80b2\u60c5\u51b5\u7b49\u3002
<\/p>\n\n\n
![\"\"](\"http:\/\/106.52.84.14\/wp-content\/uploads\/2025\/04\/image-85-4-19-1-1.jpg\")
<\/figure>\n<\/div>\n\n\n\u56fe3. iSeg-2017\u6311\u6218\u8d5b\u65b9\u6cd5(MSL_SKKU)\u548c\u4eba\u5de5\u5206\u5272\u7684\u7ed3\u679c\u5206\u522b\u4e3a\u7b2c1\u884c\u548c\u7b2c2\u884c\u3002\u4ece\u5de6\u5230\u53f3\uff1aT1\u52a0\u6743\u548cT2\u52a0\u6743\u56fe\u50cf\u4e0a\u7684\u5206\u5272\u7ed3\u679c\uff0c\u5185\u76ae\u8d28\u8868\u9762\uff0c\u76ae\u8d28\u539a\u5ea6\u56fe\uff0c\u5185\u76ae\u8d28\u8868\u9762\u548c\u76ae\u8d28\u539a\u5ea6\u56fe\uff08\u6beb\u7c73\uff09\u7684\u5c40\u90e8\u653e\u5927\u56fe\u3002<\/p>\n\n\n\n
\u5176\u6b21\uff0c\u6240\u6709\u65b9\u6cd5\u90fd\u5ffd\u7565\u4e86\u8111\u810a\u6db2\u548c\u7070\u8d28\u4e4b\u95f4\u7684\u7ec4\u7ec7\u5bf9\u6bd4\u5ea6\u8fdc\u9ad8\u4e8e\u7070\u8d28\u548c\u767d\u8d28\u4e4b\u95f4\u7684\u7ec4\u7ec7\u5bf9\u6bd4\u5ea6\u3002\u56e0\u6b64\uff0c\u4ece\u5a74\u513f\u8111MRI\u4e2d\u9996\u5148\u5206\u5272\u51fa\u8111\u810a\u6db2\u7528\u4ee5\u91cd\u5efa\u5916\u76ae\u8d28\u8868\u9762\uff0c\u5e76\u5728\u6b64\u57fa\u7840\u4e0a\u4f30\u8ba1\u4e00\u5b9a\u8303\u56f4\u5185\u7684\u5185\u76ae\u8d28\u9762\uff0c\u8fd9\u79cd\u7b56\u7565\u662f\u5408\u7406\u6709\u6548\u7684[1,2]\u3002<\/p>\n\n\n\n
\u7b2c\u4e09\uff0c\u6240\u6709\u65b9\u6cd5\u5904\u7406\u6709\u8fd0\u52a8\u6a21\u7cca\u7684\u56fe\u50cf\u5747\u6548\u679c\u4e0d\u4f73\u3002\u8fd0\u52a8\u6a21\u7cca\u5728\u91c7\u96c6\u5a74\u513f\u8111MR\u56fe\u50cf\u8fc7\u7a0b\u4e2d\u5f88\u5e38\u89c1\uff0c\u56e0\u6b64\u5728\u8bad\u7ec3\u96c6\u4e2d\u52a0\u5165\u6a21\u62df\u8fd0\u52a8\u4f2a\u50cf\uff0c\u80fd\u6709\u6548\u5730\u589e\u5f3a\u7f51\u7edc\u7684\u9c81\u68d2\u6027\u3002<\/p>\n\n\n\n
\u7b2c\u56db\uff0c\u901a\u8fc7\u4ece\u90a3\u4e9b\u5bb9\u6613\u51fa\u9519\u7684\u533a\u57df\u4e2d\u9009\u62e9\u66f4\u591a\u7684\u8bad\u7ec3\u6837\u672c\uff0c\u53ef\u4ee5\u8fdb\u4e00\u6b65\u63d0\u9ad8\u8fd9\u4e9b\u5206\u5272\u7b97\u6cd5\u7684\u6027\u80fd\u3002\u524d8\u540d\u7684\u65b9\u6cd5\u4e2d\u4f7f\u7528\u7684\u8bad\u7ec3\u56fe\u50cf\u5757\u5927\u5c0f\u4ece24\u00d724\u00d724\u523080\u00d780\u00d780\u4e0d\u7b49\uff0c\u56e0\u6b64\u5982\u4f55\u9009\u62e9\u6700\u4f18\u7684\u56fe\u50cf\u5757\u5927\u5c0f\u4e5f\u662f\u4e00\u4e2a\u91cd\u8981\u7684\u7a81\u7834\u70b9\u3002
\u6700\u540e\u9488\u5bf9\u591a\u4e2a\u7ad9\u70b9\u91c7\u96c6\u7684\u56fe\u50cf\u7684\u5206\u5272\u96be\u9898(Multi-site segmentation): \u5728\u4e00\u4e2a\u6570\u636e\u96c6\u4e0a\u8bad\u7ec3\uff0c\u5728\u591a\u4e2a\u6570\u636e\u96c6\u4e0a\u6d4b\u8bd5\uff0c\u6211\u4eec\u7ec4\u7ec7\u4e86iSeg-2019\u6311\u6218\u8d5b(http:\/\/iseg2019.web.unc.edu\/)\uff0c\u6b22\u8fce\u5927\u5bb6\u53c2\u52a0\u3002
\u539f\u6587\u8bf7\u53c2\u89c1\uff1ahttps:\/\/ieeexplore.ieee.org\/document\/8654000
Li Wang, Dong Nie, Guannan Li, \u00c9lodie Puybareau, Jose Dolz, Qian Zhang, Fan Wang, Jing Xia, Zhengwang Wu, Jiawei Chen, Kim-Han Thung, Toan Duc Bui, Jitae Shin, Guodong Zeng, Guoyan Zheng, Vladimir S. Fonov, Andrew Doyle, Yongchao Xu, Pim Moeskops, Josien P.W. Pluim, Christian Desrosiers, Ismail Ben Ayed, Gerard Sanroma, Oualid M. Benkarim, Adri\u00e0 Casamitjana, Ver\u00f3nica Vilaplana, Weili Lin, Gang Li, and Dinggang Shen. “Benchmark on Automatic 6-month-old Infant Brain Segmentation Algorithms: The iSeg-2017 Challenge.” IEEE Transactions on Medical Imaging, 38(9), 2219-2230, 2019<\/p>\n\n\n\n
1. Wang et al., “Volume-Based Analysis of 6-Month-Old Infant Brain MRI for Autism Biomarker Identification and Early Diagnosis,” in MICCAI, 2018, pp. 411-419.
2. Wang et al., “Anatomy-Guided Joint Tissue Segmentation and Topological Correction for 6-Month Infant Brain MRI with Risk of Autism,” Human Brain Mapping, vol. 39, pp. 2609-2623, Jun 2018.
3. Li et al., “Computational Neuroanatomy of Baby Brains: A Review.” NeuroImage, vol. 185, pp. 906-925, 2019.
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